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Abstract The preliminary results of an international collaborative study examining premature menopause in fragile X carriers are presented. A total of women from fragile X families was surveyed about their fragile X carrier status and their menstrual and reproductive histories. Among the subjects, carried a premutation, carried a full mutation, and were noncarriers. Based on these preliminary data, there is a significant association between fragile X premutation carrier status and premature menopause. Finally, Partington et al.
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Fragile X Premutation Is a Significant Risk Factor for Premature Ovarian Failure

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